Rapid Troponin I Detection Kit

Troponin I (cTnI) is a protein with a molecular weight of 22.5 kDa, forming part of a tripartite complex that includes Troponin C, Troponin T, and Troponin I. This structural tripartite complex, along with tropomyosin, regulates the main calcium-sensitive ATPase activity of actomyosin in skeletal and cardiac striated muscles. Following cardiac injury, cTnI is released into the blood within 4-6 hours after the onset of pain. The pattern of cTnI elevation is similar to that of MB-CK, with the difference being that MB-CK returns to its normal level after 72 hours, while cTnI remains elevated for 6 to 10 days, providing a longer time window for diagnosing cardiac muscle damage. The higher specificity of the troponin test in diagnosing cardiac muscle damage has been examined and observed in conditions such as pre-cardiac surgery, after marathons, and chest trauma. cTnI release into the blood also occurs in other cardiac conditions, including unstable angina, congestive heart failure, and ischemic injury following bypass surgery. Currently, due to the high specificity and sensitivity of Troponin I in heart tissue, this test has become the most popular biomarker for myocardial infarction.